OBJECTIVES: Evaluate the relative impact of migraine-related outcomes using generalized healthy-time equivalences (HTE). METHODS: A best-practice conjoint analysis or discrete-choice experiment (DCE) evaluated migraine-related outcomes reported in the Completeness of Response Survey (CORS). We elicited patients’ trade-off preferences for migraine symptoms with different clinically relevant durations, including symptom-free time. Preference-parameter estimates were used to determine the amount of symptom-free time that was utility-equivalent to 24-hour migraine episode profiles described by acute headache, post-headache, and symptom-free phases. These HTEs quantify the impact of migraine-related outcomes using a fully general utility-theoretic conceptual framework. Unlike quality-adjusted life years (QALYs), HTEs do not require assuming that utility of a brief, but severe, outcome is a simple fraction of a quality-adjusted year. Also unlike QALYs, HTEs do not require risk neutrality, and easily account for personal characteristics that may determine preferences for health outcomes. RESULTS: A total of 539 people with a self-reported physician diagnosis of migraine completed the survey. As expected, migraineurs were negatively affected by the duration of headache-phase and post-headache-phase symptoms. However, for some groups in the sample we found no statistical difference in relative preferences for different pain severities in the acute headache phase. Subjects had clear preferences for different levels of daily-activity limitations experienced during the post-headache phase. Results also showed that subjects in the sample were averse to risk. We also found preference heterogeneity based on individual characteristics.  CONCLUSIONS: This study demonstrates the feasibility of obtaining standardized healthy-time equivalences derived from clinically-relevant symptom-duration tradeoff data as a feasible alternative to QALYs for acute, self-limiting conditions.  The results also suggest that the assumptions associated with the use of conventional QALYs are not met by our sample of migraineurs; adding to the mounting body of evidence that encourages the use of more flexible utility-theoretic measures of quality-adjusted time.