Objective: To determine the demographic, insurance, and health status predictors of noncompliant cost-cutting behavior among U.S. adults. Methods: Data were from quarters one and two of the 2007 National Health and Wellness Survey (NHWS), an internet-based study of the healthcare attitudes, behaviors, disease states, and outcomes of a demographically representative sample of adults age 18+. Noncompliant cost-cutting behaviors were defined as taking less medication than prescribed, cutting tablets in half, or buying fewer tablets. Logistic regression analysis was used to determine the demographic, insurance, and health status predictors of noncompliant cost-cutting behavior. Results: Of the 42,010 NHWS respondents, 12% reported some noncomplaint cost-cutting behavior, more specifically 7% reported taking less medication than prescribed, 6% reported cutting tablets in half, and 2% reported buying fewer tablets. Significant predictors of greater likelihood of noncompliant cost-cutting behavior include being non-white (OR=1.182, p<0.001), having a college degree (OR=1.094, p=0.009), having individual or family insurance purchased directly (OR=1.300, p<0.001), purchasing medications outside the U.S. (OR=3.862, p<0.001), number of physical comorbid conditions (OR=1.176, p<0.001), having a psychiatric condition (OR=1.620, p<0.001), currently smoke (OR=1.137, p<0.001), and body mass index (OR=1.006, p=0.007). Significant predictors of lesser likelihood of noncompliant cost-cutting behavior include age (OR=0.996, p=0.001), having insurance through the Veteran's Administration (OR=0.514, p<0.001), and having Rx coverage (OR=0.808, p<0.001). Gender, marital status, annual income greater than $50,000, number of adults in household, and insurance through employer, Medicaid, or Medicare were not significant predictors of non-compliant cost cutting behavior. Conclusion: There are several significant predictors of noncompliant cost-cutting behavior. Knowing these predictors may help in targeting cost savings and compliance programs at those who need them the most.