OBJECTIVES: The aim of the present study was to evaluate the effect of 700mg and 1400mg pomegranate seed capsules on body weight and blood pressure for a period of 60 days at time interval 7, 14, 21, 28, 45 and 60 days respectively. METHODS: At the beginning of the study twenty four healthy human volunteers were selected. On the basis of BMI two broader groups, i.e. group 1 taking 700mg pomegranate capsules and group 2 taking 1400mg pomegranate capsules were designated and both the groups were subdivided on the basis of diet control and exercise i.e. group1 (IA, IB) and group 2(IIA, IIB). Group IA and IIA took pomegranate capsules without diet and exercise while IB and IIB took the capsules with diet and exercise. Hypertensive patients from these groups were included in both groups who were categorized and evaluated separately and compared with normal individuals. RESULTS: The result of investigation indicated that both doses of pomegranate seeds capsules had significantly reduced the body weight and blood pressure profile (both systolic and diastolic) in all groups when compared with their baseline values. However both doses caused equal reduction of body weight and blood pressure as no significant difference was present in both doses (p-value > 0.05). CONCLUSIONS: Thus on the basis of results obtained after conducting our study it was concluded that pomegranate seed capsules have established their efficacy and safety profile for obesity control and hypertension management.