OBJECTIVES: To carry out the psychometric validation of the Spanish version of the self-administered TBS scale, a tool assessing subjective outcomes in the treatment of subjects with overactive bladder (OAB).  METHODS: The culturally adapted Spanish version of TBS was administered at the end-of-trial visit after 3 months of a medical intervention for OAB. Responses to the instruments were recorded in a set of patients of  both genders, above 18 years old, diagnosed of OAB according with standard criteria and a score > 8 in the OAB-V8 scale, and able to understand PRO instruments written in Spanish. Patients were recruited consecutively in clinics of Urology all over the country. Scale variability, criteria, known-groups and construct validity and responsiveness (effect size) were examined using classic test theory statistics.  RESULTS: Data from 199 OAB patients (58.4 years, 74% women, 99% Caucasian, 37% workers and 36% primary schooling) from 18 urological clinics were evaluated. The 2.5% of patients did not fill  in the scale, only 31% greatly improved, 57% improved, 10% did not changed and 2% worsened during medical intervention. TBS correlated moderately with clinical judgement of change; 0.749, p<0.001, and also, linearity was observed, with changes at end-of-trial visit in both domains of the OABq-SF; Flineal=23.02, p<0.001 and Flineal=31.02, p<0.001. TBS was able to differentiate groups of patients with different levels of change in symptoms severity and health-related quality of life of the OABq-SF questionnaire; F=8.09, p<0.001 and F=10.5, p<0.001, respectively, with effect sizes between 1.69 and -0.44. CONCLUSIONS: The Spanish version of TBS scale demonstrated strong validity and responsiveness psychometric properties to be used in the subjective assessment of outcomes related with treatment of OAB.