OBJECTIVES: To develop targeted leaflets regarding cancer screening guidelines that take account the knowledge required by different target groups.  METHODS: Before developing leaflets, public interest data regarding cancer screening was collected by the problem solving model (the so-called KJ method developed for field surveys in Japan). The KJ method includes two steps: label making of information corresponded to specific issues and grouping similar concepts. Contents of leaflets were edited based on the results of the KJ methods but changed in the final version according to discussions at a committee meeting involving public members. We compared the results of the KJ method and contents of the final version of the leaflets for the following groups: cervical cancer screening targeted at 20-years-old subjects (first group), cervical cancer screening targeted at subjects aged 30 years and older (second group), and colorectal cancer screening targeted at subjects aged 40 years and older (third group). RESULTS: Common interests among the three groups included targeting cancer and screening methods. Although the KJ method revealed that the first group expected broad information, in the final version of the leaflet, only basic information regarding participation in cancer screening programs remained. The final versions in group 2 and 3 almost corresponded to the first interest of an actual plan to participate in a screening program including details of the screening methods as well as physical and financial burden expected. Although information regarding the harm of cancer screening was initially included according to the results of the KJ methods in the second and third groups, there was no expectation in the first group.  CONCLUSIONS: A targeted leaflet is a powerful tool to share knowledge regarding cancer screening. We must understand the expectations of different target groups and prepare appropriate leaflets that support the decision to take part in cancer screening.