BLOOD PRESSURE CONTROL AND ANTIHYPERTENSIVE STRATEGY DIFFERENCES ACCORDING TO PATIENTS AGE

Author(s)

Font B1, Galera J2, Lahoz R3, Muñoz G2, Sierra C4, Doménech M4, Coca A41Novartis Pharma, Barcelona, Spain, 2Novartis Pharma, Barcelona, Barcelona, Spain, 3Novartis Farmacéutica S.A., Barcelona, Barcelona, Spain, 4Hospital Clínic de Barcelona, Barcelona, Barcelona, Spain

OBJECTIVES: This study aims to determine the degree of blood pressure (BP) control and the differences in therapeutic strategies adopted by physicians based on patients’ age and/or their functional status. METHODS: Multicenter and cross-sectional study that included patients with essential hypertension attending primary or specialist care, with at least one year of evolution. The study included 6453 patients, stratified into three main groups: A (<65 years) = 2184; B (65-79 years) = 2079; and C (≥80 years) = 2079. RESULTS: 51.3% of patients were male and mean (SD) age was 55.1±7.5 years (group A), 71.4±4.0 (B) and 83.7±3.2 (C). 49.1% of patients were overweight. Mean systolic BP values were 141.3±15.6 (A), 142.0±16.3 (B) and 142.3±16.8 (C) mmHg, and mean diastolic BP values were 84.5±10.1 (A), 81.5±10.5, 79.9±11.2 (C) mmHg. 33.5% of patients had type 2 diabetes mellitus and 59.1% dyslipidemia. The existence of previous cardiovascular (CVD) or renal disease has been established in 38.9% of cases. The prevalence of CVD was 22.6% (A), 39.1% (B) and 55.9% (C). Target organ damage (TOD) was 26.7% (A), 40.8% (B) and 57.8% (C). The Barthel index that measures a person's daily functioning reflected that the oldest group had a significantly higher level of moderate or severe dependence (p<0.0001). Patients with controlled BP were 29.4% (A), 25.5% (B) and 23.7% (C) (p<0.0001). Clinical inertia –the failure to intensify therapy in patients who do not achieve the clinical objectives– reached 60.3% (A), 61.7% (B) and 66.2% (C) (p=0.0002), respectively. Global treatment compliance was 94.3%, and the difficulty for taking the medication significantly increased with patients’ age (p<0.0001). CONCLUSIONS: Older hypertensive patients have a poorer BP control but an increased clinical inertia. These patients have higher prevalence of TOD and CVD, worse functional status and worse treatment compliance.

Conference/Value in Health Info

2010-11, ISPOR Europe 2010, Prague, Czech Republic

Value in Health, Vol. 13, No. 7 (November 2010)

Code

PCV31

Topic

Epidemiology & Public Health

Disease

Cardiovascular Disorders

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