OBJECTIVES: The aim of this study was to determine the reliability and validity of the Social Functioning Scale (SFS) for the Turkish MSDs (Musculoskeletal disorders) patients. METHODS: The scale, which was translated into English from Turkish, again translated back into English by two independent translators, was applied to 32 MSDs patiets for pre-test. Non working questions applied to a target group were re-tested and then the scale was applied to the bulk of subjects (N=82). Cronbach’s Alfa was used to assess reliability and factor analysis to assess dimensionality. The EuroQol-5D was used for concurrent validity. RESULTS: Among the patients were 15.9% ankylosing spondylitis, 6.1% rheumatoid arthritis, 24.4% osteoarthritis, 12.2% osteoporosis, 13.4% radiculitis, 9.8% fibromyalgia, 2.4% stroke, 15.9% rheumatic disease. The internal consistency coefficient (Cronbach's alpha) of SFS was 0.68. Factor analysis of the scale revealed that it was composed of three factors with Eigenvalues >1, accounting for 90.8% of the total variance. All items of the Turkish SFS had a factor load ranging from 0.40 to 0.77 There was a strong relationship between Social Functioning Scale and EuroQoL 5D. CONCLUSIONS: The Social Functioning Scale has good validity and reliability for Turkish MSDs patient.