OBJECTIVES: In Korea, not only has the number of stroke patients increased, but also the integrated western and oriental medical treatment became popular. In this study, treatment costs for stroke were compared for those with integrated treatment with the costs of western treatment. METHODS: During the period between May 2006 and February 2009, the treatment cost was analyzed for 318 stroke patients who were admitted to the emergency room of a secondary hospital. Medical records were collected and detailed cost items were compared. SAS Version 9.1 was used for data analysis. RESULTS: The estimated annual treatment cost for a stroke patient is KRW 10.55 million for the integrated treatment, whereas it is KRW 8.11 for western treatment only. The biggest parts of integrated treatment cost were for rehabilitation and oriental medical treatments. Because much of oriental treatments is not covered by health insurance, patients’ burden were heavier compared to western treatment. Oriental treatment comprises 16.3% for the inpatients, whereas higher at 65.2% for outpatients. In addition, although the incidence of ischemic stroke was higher than that of hemorrhagic stroke, the average days of hospitalization and average total treatment cost per patient were higher in the case of hemorrhagic stroke in Korea. CONCLUSIONS: The integrated medical treatment costs more than only the western treatment. However, more detailed study with more integrated treatment patients will be needed to generalize the study results.