ATOPIC DERMATITIS IN PAEDIATRIC PATIENTS- COMMON CAREGIVER BEHAVIOUR WHEN FACING THE DIFFERENT DISEASE PRESENTATIONS OR LESION SEVERITY. ELIBROT STUDY
Author(s)
Raquel Lahoz, BSc, MB, HOR Advisor1, Antonio Torrelo, MD, PhD, Doctor2, Isabel Febrer, MD, PhD, Doctor3, Marta Lleonart, MD, PhD, Medical Advisor11Novartis Pharmaceuticals, Barcelona, Spain; 2 Hospital Niño Jesús, Madrid, Spain; 3 Hospital General Universitario de Valencia, Valencia, Spain
OBJECTIVES: To assess the parents’/caregivers’ behavior of the pediatric patient with atopic dermatitis (AD) stratified by type, severity and flare-up area. METHODS: An epidemiological, cross-sectional study in patients 2-12 years old with mild or moderate AD and at least two flares in the previous year, were conducted in 451 paediatric sites. Patient characteristics and a brief clinical history were asked to caregivers. Data about the management and characteristics of flares were requested to caregivers. The satisfaction with treatment use was also requested. A logistic regression was performed to analyze the predictive factors of worries to use corticosteroids. Moreover, the odds ratio (OR) of them were calculated. RESULTS: A total of 1177 patients were included. A total of 52.3% boys with a mean (SD) of 5.3(2.8) years old. A total of 66.4% of patients had family history of AD, two third of them were parents. The mean (SD) age at diagnosis was 1.6 (1.5). The lesions are mainly presented in upper and lower extremities and face/neck (>70%). The parents’/caregivers’ visits to the doctor was six times greater for moderate episodes vs mild ones (OR=6.15, IC95%:5.12–7.14; p<0.0001). Regarding visits according to age, there were an 8% visits decrease for each year of age (OR=0.92, IC95%:0.89–0.96; p<0.0001). A total of 19.3% of caregivers never use corticosteroids in lesions on face/neck, and 52.4% could use it only as an alternative option. However, when lesions are presented in other parts of body, 48.9% of caregivers use it as first line option. The most commonly used treatments are moisturizing products (31.0%), topical immunomodulators (30.3%) and strong corticosteroids (23.3%). There are three predictive factors related to avoid use of corticosteroids: location in face/neck (OR=4.47, IC95%:3.50–5.72), mild severity (OR=1.98, IC95%:1.48–2.66) and low age (OR=0.94, IC95%:0.88–0.99). CONCLUSIONS: Parents/caregivers have serious worries to use corticosteroids in children with flares in face/neck, with mild severity and in younger childrens.
Conference/Value in Health Info
2008-11, ISPOR Europe 2008, Athens, Greece
Value in Health, Vol. 11, No. 6 (November 2008)
Code
PSS53
Topic
Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes
Disease
Sensory System Disorders