Leveraging Time-Use Data to Estimate Market and Non-Market Productivity Losses Due to Respiratory Syncytial Virus (RSV) Disease Among Adults Aged ≥60 Years in the United States (US)
Author(s)
Verelst F1, La E2, Graham J3, Molnar D1
1GSK, Wavre, WBR, Belgium, 2GSK, Raleigh, NC, USA, 3RTI Health Solutions, Durham, NC, USA
Presentation Documents
OBJECTIVES: In economic analyses, productivity losses are often limited to wages lost due to missed work. However, among older adults, risk of severe RSV infection increases with age, where market productivity is limited to those remaining in the workforce. This study estimates market and non-market productivity losses due to RSV cases and premature mortality in US adults aged ≥60 years.
METHODS: To estimate age-specific productivity losses, RSV-relevant time losses were obtained from published data (0.5–1 day for nonmedically-attended RSV cases, 3.3 days for outpatient cases, and 7 days for hospitalized cases). American Time Use Survey data were analyzed to assign these time losses to market productive, non-market productive, or non-productive time, which were then valued at their respective unit costs. Productivity losses due to RSV premature death were obtained from the literature, with total RSV productivity losses estimated using a Markov-cohort model.
RESULTS: Older adults spend less time performing market vs. non-market productive activities (e.g., 1.5% vs. 16.8% for those aged ≥75 years). RSV lower respiratory tract disease cases are associated with market productivity losses that decline with age (from $275 to $32 for adults aged 60–64 vs. ≥75 years); non-market productivity losses peak at age 65–74 years ($195). RSV upper respiratory tract disease cases also incur significant productivity losses (market: $17–$156; non-market: $74–$114). Discounted lifetime productivity losses due to RSV deaths were highest for 60–64-year-olds (market: $322,286; non-market: $380,945). Annual productivity losses of RSV acute cases amount to nearly $700 million, with productivity losses due to RSV deaths contributing an additional nearly $4 billion.
CONCLUSIONS: In addition to clinical and direct economic burden, RSV causes nearly $4.7 billion in productivity losses among US older adults annually. Capturing both market and non-market productivity losses more comprehensively reflects older adults’ value to society.
Funding: GlaxoSmithKline Biologicals SA (VEO-000554)Conference/Value in Health Info
Value in Health, Volume 26, Issue 6, S2 (June 2023)
Code
EE331
Topic
Economic Evaluation
Topic Subcategory
Work & Home Productivity - Indirect Costs
Disease
No Additional Disease & Conditions/Specialized Treatment Areas