Introduction: During the COVID pandemic, the medical oncology department of the Hospital Establishment DIDOUCHE Mourad, Constantine, launched a vaccination campaign for eligible patients, during the vaccination campaign initiated by the Ministry of Health.

Materials and Methods: Faced with the risk of contracting the severe form of COVID19 in patients with cancer, the team of the medical oncology department thought of this type of patients and developed a well-established vaccination protocol for patients with cancer. This vaccination protocol respected all barrier measures while taking certain precautions to eliminate patients who would be carriers of an asymptomatic COVID-19 infection or whose symptoms would be like oncology emergencies.

Results: Out of 379 patients who came to the department during these five days, 201 patients agreed to be vaccinated, representing a percentage of 53.03% and only 180 patients (47.49%) were vaccinated (due to lack of sufficient quantity of vaccines at our level during these five days and the high adherence of patients)), against 8.97% of refusal (34 patients). The remaining patients (37.9%) had either absolute or non-absolute contraindications to vaccination or had contracted a recent COVID infection; delaying the vaccination to 3 months. Only one side effect (0.55%) was noted; that of hypoglycemia in a patient who presented on an empty stomach to the ward

All these patients (100%) agreed to be vaccinated in the oncology department and refused to join the vaccination site opened within the establishment because of a relationship of trust - security established between patients-attending physicians

Conclusion: Medical work department and preventive epidemiology services should continue to vaccinate health personnel and the population; eligible respectively but the category of eligible patients (which is no longer an eligible person but an eligible patient); and especially patients with chronic diseases should be cared for in treatment’s centers according to patients' choices