Healthcare Utilization and Charges Associated with US Hospitalized Adult Patients with Coronavirus Disease 2019
Author(s)
Richards F1, Munoz B2, Fried MW2, Morris HL3, Mospan AR2, Crawford JM4, Patterson B5, Di Scala L6, Holy C7, El Khoury AC8
1Janssen Global Services, Rahway, NJ, USA, 2Target RWE Health Evidence Solutions, Chapel Hill, NC, USA, 3Target RWE Health Evidence Solutions, Gainesville, FL, USA, 4Target RWE Health Evidence Solutions, Austin, TX, USA, 5Janssen Global Services, Basking Ridge , NJ, USA, 6Janssen Global Services Health Economics & RWE, Allschwil, BL, Switzerland, 7Johnson & Johnson, Somerville, MA, USA, 8Janssen Global Services, Raritan, NJ, USA
Presentation Documents
Objective: This project aims to investigate the total hospital charges and identify the characteristics associated with health services provided to COVID-19 inpatients hospitalized across the US. Methods: This retrospective, observational study utilized US hospital chargemaster deidentified data from 330 hospitals from April to December 2020. The ICD-10 code U07.1 was used to identify patients with COVID-19. Demographic data were analyzed descriptively and linked with total charges. A predictive model for total hospitalization charges related to the first hospitalization with generalized estimating equation estimates was developed to model the association between hospital charges and patient-level clinical and demographic variables available at admission and hospital characteristics. Results: A total of 152,773 patients were included. The median length of stay was 7 days. The majority of patients were aged 60+ (61%) and males (53%). 16% of patients required a stay in the ICU with a median duration in the ICU of 8 days (min-max: 1-193 days). 50% of patients were diagnosed with pneumonia within the first 24 hours of admission and 81% were diagnosed at some point during hospitalization. Within 24 hours of admission, 54% of patients required supplemental low flow oxygen. Adults 60+ ($58,112, min-max = $1,097-$3,652,729), males ($57,131, min-max = $1,005-$4,324,068) and Hispanics ($61,997, min-max = $1,057 - $4,324,068), had the highest median total charges within each of the demographic categories. The median total charges for all patients were $52,821 (min-max= $1,005-$4,324,068). A predictive model for total COVID-19 hospitalization charges estimated the average total charges as $75,517 (95% CI = $53,559 - $97,475). Charges were higher in male patients ($19,781, p<.0001) and those with a higher Elixhauser comorbidity index score ($1,841, p<.0001). Conclusions: Our findings confirm that COVID-19 hospitalizations were associated with significant resource utilization. Increased charges were associated with elderly age, male sex, Hispanic ethnicity, and multiple comorbidities.
Conference/Value in Health Info
2022-05, ISPOR 2022, Washington, DC, USA
Value in Health, Volume 25, Issue 6, S1 (June 2022)
Code
EE334
Topic
Economic Evaluation
Disease
Vaccines