Objectives: Female infertility is a global medical condition that could be caused by various disorders of the reproductive system. Female infertility constitutes a significant and growing burden on patients, health care systems and the society. Our aim was to determine the annual costs of the health insurance system related to the unspecified female infertility in Hungary.

Methods: Data were derived from the financial database of the National Health Insurance Fund Administration of Hungary, of the year 2019. Data analyzed included annual health insurance costs, patient numbers and cost distribution calculated for age groups. The following cost categories were included into the study: general practice care, home care, in- and outpatient care, medical imaging, laboratory diagnostics, pharmaceuticals and medical aids. Patients with unspecified female infertility were identified with the following code of the International Classification of Diseases 10^th revision: N9790.

Results: In 2019, the Hungarian National Health Insurance Fund Administration spent 5.138 billion Hungarian Forints (HUF) on the treatment of patients with unspecified female infertility, 17.68 million American Dollars (USD), or 15.79 million Euros (EUR). The highest patient numbers were in outpatient care (26,160 women). Inpatient care (53.0% of total health insurance costs) utilization of pharmaceuticals (40.6%) and outpatient care (3.2%) were the main cost drivers, while all other forms of medical care amounted to 3.2% in women. Annual health care treatment cost per patient was 196,384 HUF (676USD/604 EUR) according to number of patients related to outpatient care. The highest annual health insurance costs were found in the ‘30-39’ and ‘40-49’ age groups.

Conclusions: The utilization of inpatient care was the major cost driver, which was 1.39 times higher than use of pharmaceuticals, 16.56 times as much as outpatient care costs in 2019. The proportion of the costs of the treatment showed a significant difference among age groups.