The aim of this study was to analyze all costs of beneficiaries appointmented in a telemedicine service of a health care provider in the State of Paraná- Brazil. We performed a real-world, retrospective chart review using data from the health insurance company database (South region in Brazil) to identify patients with COVID-19 who performed a medical consult by the telemedicine service between May 2020 and May 2021, until 12 months after diagnosis of Covid-19. Demographic, clinical data and costs (currency quote: US$ 1= R$ 5.69) of exams and treatments/hospitalization were extracted. Descriptive statistics were conducted with results reported as percentage. A total of 195 patients tested positive for Covid-19, 7 were excluded because they had no recorded costs, so we included 188 patients who used the telemedicine service during the period. Of these, 61.70% (n=116) patients were female and 29.8% (n=56) were between 31 and 40 years old. The average cost per patient after Covid-19 was USD 1,594.02 (total USD 322,784.17). 9% (n=17) of the patients required hospitalization, and of these 41.2% (n=7) were hospitalized from 1 to 7 days. Most of resources were consumed during the second quarter of 2021 with post-Covid-19 patients (USD 157,663.41). In addition, among the expenditure, the most used specialty was the general hospital, begetting a cost of USD 134,131.57 in the period. There is a high economic impact for health care providers after diagnosis of Covid-19, it may be associated to the late symptoms and complications of the disease, and that this can impact both private and public health. The knowledge of costs after Covid-19 and its consequences in different population profiles can help in the development of a comprehensive approach for better decision-making and strategic planning in the organization of care networks and the programming of health actions.