OBJECTIVES. Several prospective studies - have indicated that the TECNIS Symfony, an extended depth of focus (EDOF) intraocular lens (IOL), achieves excellent visual outcomes at all distances after cataract surgery. The purpose of this study was to combine the visual outcomes from multiple recent studies of the TECNIS Symfony ZXR00.

METHODS. We performed a systematic literature review and subsequent data pooling of studies looking at corrected visual outcomes for patients within 6 months (range: 3-6 months) of receiving bilateral implantation of TECNIS Symfony IOLs following cataract surgery. The primary visual quality outcome of interest was accommodation measured by defocus curves. Data from monocular and binocular defocus curves were extracted and then pooled using a weighted average approach. Separate pooled curves were estimated for monocular and binocular data.

RESULTS. We identified 25 articles of potential interest in the database review; 7 of these included TECNIS Symfony defocus curves. Of these, 3 provided monocular defocus curves (total eyes = 130), and 6 provided binocular defocus curves (total eyes = 310). The pooled defocus curves showed best corrected visual acuity generally remained high (LogMar ≤ 0.2) from 1.0 diopters (D) to -2.0 D in patients who received TECNIS Symfony IOLs. For the pooled monocular defocus curve, the corrected distance visual acuity (0 D) was LogMar-0.04, the corrected intermediate visual acuity (66cm; -1.5 D) was LogMar0.13, and the corrected near visual acuity (40cm; -2.5 D) was LogMar0.40. For the pooled binocular defocus curve, the corrected distance visual acuity was LogMar-0.02, the corrected intermediate visual acuity was LogMar0.11, and the corrected near visual acuity was LogMar0.34.

CONCLUSIONS. The TECNIS Symfony EDOF IOL provides successful visual restoration across all distances after cataract surgery, with a minimal level of disturbing photic phenomena and high levels of patient satisfaction.