OBJECTIVES: Adverse drug reactions (ADRs) are major health problems which has global concern. Spontaneous reporting of adverse drug reactions are known to have a crucial contribution to patient care. The purpose of this study was to assess the knowledge, attitudes, and practices of healthcare professionals towards adverse drug reaction reporting.

METHODS: A cross-sectional study was conducted from March to May 2017 at Gondar town, Ethiopia. Data were collected through self-administered questionnaires. The collected data were analyzed using SPSS version 20. Binary logistic regression analysis was performed to distinguish factors that affect adverse drug reaction reporting. A p-value <0.05 was considered as a statistically significant.

RESULTS: Of hundred two healthcare professionals included in this study 61 (59. 8%) were Nurses, 16 (15.7%) Health Officers, and 25 (24.5%) Pharmacy Professionals. Nearly half 48 (47%) of the study participants had an inadequate level of knowledge towards adverse drug reaction reporting. The majority of participants 88 (86.3%) had a positive attitude. While more than half 29 (51%) of study participants did not report the adverse drug reaction they encountered. Participants who had not taken adverse drug reaction reporting training (p=0.037), Health Officers (p=0.019) and Nurses (p=0.001) professionals were exhibited a statistically significant association with an inadequate level of knowledge.

CONCLUSIONS: Even though the majority of healthcare professionals had a positive attitude, they had an inadequate level of knowledge and practice towards adverse drug reaction reporting.