Author(s)
Salcedo Mejía FE1, Miranda PA2, Vargas R3, Parra Padilla D4, Paz-Wilches J5, Alvis-Guzman N6, De La Hoz F7, Alvis Zakzuk J8, Fernandez Mercado JC9, Alvis-Zakzuk NR10
1Alzak Foundation. Universidad de Cartagena., Cartagena de Indias, Colombia, 2ALZAK Foundation. University of Cartagena., Cartagena, Colombia, 3ALZAK Foundation. University of Cartagena., Barranquilla, Colombia, 4ALZAK Foundation. University of Cartagena., Cartagena, BOL, Colombia, 5Mutual SER EPS, Cartagena, Colombia, 6ALZAK Group, Cartagena, BOL, Colombia, 7Universidad Nacional de Colombia, Bogota, Colombia, 8ALZAK Foundation, Centro de investigación Seguridad Materna - Grupo de investigacion para la salud materna, perinatal y de la mujer - Clínica Maternidad Rafael Calvo, Cartagena, Colombia, 9Mutual SER EPS, CARTAGENA DE INDIAS, Colombia, 10ALZAK Foundation, Cartagena, Colombia
OBJECTIVES : To establish the association between the exposure to a cardiovascular risk management program [“De Todo Corazon (DTC)” program in Mutual SER-EPS] and the reduction of incidence and mortality by cardiovascular events (CVE: AMI, Stroke, congestive heart failure) METHODS : Cohort study that compared the occurrence of CVE among patients over 18 years of age exposed and non-exposed to the DTC program (N = 113,277). Enrolled patients in the DTC program between June 2015 and June 2017 were considered as the exposed population and patients enrolled in the DTC program between July 2017 and July 2018 were considered as the unexposed population. Patients who achieved clinical goals (blood pressure <140/90 mmHg, HbA1c <7.5% and LDL cholesterol <100 mg/dl) were considered adherent to the DTC program. Incidence and mortality rates were compared and Incidence rate ratio (IRR) was used to evaluate the effect of the program. A Poisson regression model was used to assess the association between exposure to the program and CVE adjusting by socio-demographic characteristics and clinical goals RESULTS : The incidence of CVE in exposed and unexposed patients was 6.8 and 9.5 per 1.000 persons per year, respectively [IRR of 0.72 (95% CI 0.60-0.87)]. Mortality associated to CVE in exposed and unexposed patients was 0.46 and 0.56 per 1.000 persons per year, respectively [IRR 0.82 (95% CI 0.40-1.95)]. When adjusting the estimation by age, sex and achievement of clinical goals, a lower incidence rate of CVE among patients who were adherent to the program was observed [IRR = 0.62 (CI 95% 0.46 - 0.86)]. CONCLUSIONS : Exposure to the DTC program significantly decreased the incidence and mortality CVE by 28% and 18%, respectively. Adherence to the DTC program significantly decreased the incidence of CVE by 38%.
Conference/Value in Health Info
2019-05, ISPOR 2019, New Orleans, LA, USA
Value in Health, Volume 22, Issue S1 (2019 May)
Code
PCV17
Topic
Clinical Outcomes, Epidemiology & Public Health
Topic Subcategory
Clinical Outcomes Assessment, Public Health
Disease
Cardiovascular Disorders