OBJECTIVES: To assess knowledge, attitudes, and practices towards generic pharmaceuticals (generics) amongst patients, members of Patient Associations (PAs) in Greece.

METHODS: An online survey elicited knowledge, attitudes, and practices regarding generics in Greece. Participants were registered members of PAs in Greece and received an email invitation containing a link to the survey by the Greek Patients’ Association. All responses were anonymous.

RESULTS: A total of 100 patients participated in the survey. Of them, 63% were women and 76% were 35 - 64 years old. 84% held a bachelor’s degree or higher. 67% were currently employed. 96% knew of generics and 91% knew they contain the same active substance as originators. 82% knew that generics have the same effectiveness as originators, and 45% that generics are as safe as their originator. 62% perceived generics to be manufactured in high-quality facilities. 90% considered generics important, irrespective of personal or family income, and 91% suggested patients should be free to select between generics and originators. In line with this, 75% perceived that social insurance should not mandate use of generics. Almost half (49%) of respondents perceived a switch from originator to generic to have no impact on clinical outcomes. 72% had ever been prescribed a generic, 58% had switched treatment from originator to generic, mostly on doctor’s recommendation, and 63% would be willing to switch to a generic in the future.

CONCLUSIONS: Members of PAs in Greece exhibit high levels of knowledge, acceptance, and use of generics. Further strengthening public awareness of safety and quality assurance processes for the manufacturing of generics together with additional financial incentives may contribute to increasing their voluntary uptake.