Healthcare Resource Use and Costs of Treating Patients with MDD and Suicidal Ideation or Behaviour in Europe
Author(s)
Anjo J1, Di dario G2, Herrera B3, Youssef A4, Dalibot C4, Gonzalez Martin Moro B5
1Janssen, Porto Salvo, Portugal, 2Janssen Italy, Milan, Italy, 3Janssen, Madrid, Spain, 4Janssen France, Paris, France, 5Janssen EMEA, Madrid, Spain
Presentation Documents
OBJECTIVES Patients with Major Depressive Disorder (MDD) and suicidal ideation or behaviour (MDSI) constitute a psychiatric emergency requiring urgent medical attention. Remission of MDD is one of the key treatment goals in these patients. This study aims to quantify the healthcare resource use (HRU) and costs of treating patients with MDSI in Europe, making the distinction between 2 different disease health states: remission and major depressive episode (MDE). METHODS HRU was retrospectively collected by 159 psychiatrists from France, Italy and Spain who analysed 664 medical records from adult patients diagnosed with MDSI within 12 months before the survey completion. Inpatient and outpatient HRU was mapped for periods of remission and MDE captured in records with a follow-up period of ≥6 months. Costs were derived using unit costs from specific country data sources. RESULTS Patients in MDE used emergency room services twice more and stayed 6.4 times more days in the hospital than patients in remission (43.6 vs. 6.8 days per patient/year). In outpatient setting, patients in remission used twice more resources than patients in MDE (40.7 vs. 19.2 events per patient/year). Psychiatrist visits and counselling represented >50% of the outpatient resource use in both remission and MDE states while medication use ranged from 8% in remission to 20% in MDE. Electroconvulsive therapy and transcranial magnetic stimulation were rarely used in any setting or disease state (<1 event per patient/year). The differences observed in HRU translated into a 3.4 times higher cost per patient/year in MDE compared to remission. This was largely driven by inpatient resource use, which constituted about 90% of the costs incurred by patients in MDE (vs. 50% in remission). CONCLUSIONS Disease health state drives HRU in MDSI, with a clear shift from emergency/inpatient care in MDE to outpatient care in remission. Remission represents cost savings to the healthcare system.
Conference/Value in Health Info
2021-11, ISPOR Europe 2021, Copenhagen, Denmark
Value in Health, Volume 24, Issue 12, S2 (December 2021)
Code
POSB89
Topic
Economic Evaluation
Disease
Mental Health