Attendees interested in medication adherence, the management of patients with multiple medical comorbidities, or the health and economic challenges of polypharmacy are welcome to join this forum of the Medication Adherence and Persistence Special Interest Group. A brief presentation on the main findings of the recently released systematic literature review on the methods for measuring multiple medication adherence will be followed with an open discussion on the proposed future projects of the Special Interest Group. Topics related to adherence in patients receiving polypharmacy, such as how to validate multiple medication adherence measurements using real world data and how to evaluate adherence enhancing interventions along multiple criteria will be discussed with the audience. Attendees will have the opportunity to contribute their perspectives, discuss ideas for future studies and volunteer to help activities of the Special Interest Group. Grab your lunch and join us for this informative discussion.