OBJECTIVES : To compare sleep quality and depress between student, lecturer. 2. To investigate the relationship between sleep quality and depression among three groups-student, lecturer and employee at The College of Pharmacy, Burapha University.

METHODS : A cross-sectional survey study via face to face interview was performed. Population was people of College of Pharmacy, Burapha University 2019. Sample size was calculated by Cohen’s table 1977. The α is set to 0.05, β 0.20, power 0.80, effect size 0.25 yielded n= 52 in each group. Probability simple random sampling was executed to collect all data. Instruments: 1. Pittsburgh sleep quality index (PSQI) was used to investigate insomnia in 7 aspects namely: 1) Subjective sleep quality; 2) Sleep latency; 3) Sleep duration; 4) Habitual sleep efficiency; 5) Sleep disturbances; 6) Use of hypnotic agent; and 7) Daytime dysfunction.2. Hamilton Depression Rating Scale (HAM-D) was employed to examine depression 3. Socio-economic status and medicine use data were assessed by using a single item, unidimensional questions. ANOVA and Chi Square were employed to analyze data.

RESULTS : The percentage of female in lecturer, student and employee group were 66.67%, 76.92% and 66.67%, respectively. Three groups were not significantly different in the average amount of coffee and alcohol consumption. 9.99% of lecturers used Melatonin, CPM and diazepam and 3.33% of students used diazepam for sleeping. Lecturer group was the poorest sleep and most depress than student and employee groups (p=0.02, 0.04, respectively, ANOVA). Sleep quality was significantly associated with depression (p=0.00, Chi Square).

CONCLUSIONS : We proved that Sleep quality was significantly associated with depression