Longitudinal Analyses of Health-Related Quality of Life and Daily Activities Function Among HIP Fracture Population: A Real-World Prospective Cohort Study
Author(s)
Wang CY1, Hsiao FYS2, Hung CC3, Huang CC4, Li CY5, Yang RS3, Fu SH6
1Department of Pharmacy, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan, Yunlin, Taiwan, 2Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan, 3Department of Orthopedics, National Taiwan University Hospital,, Taipei, Taiwan, 4Department of orthopedics, Cheng Ching Hospital Chung Kang Branch, Taichung, Taiwan, 5Department of Public Health, National Cheng Kung University, Tainan, Taiwan, 6Department of orthopedics, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan, Yunlin, Taiwan
OBJECTIVES : Hip fracture has been associated with increased morbidity and mortality, leading to high financial and health burden. Cost-utility analyses on hip fracture therapy are crucial, however, real world information about the longitudinal changes of patients’ health status has been limited. The study aimed to prospectively collect the longitudinal health related quality of life and daily activities function of patients with hip fracture. METHODS : It is a prospective cohort study conducted in a tertiary hospital in Taiwan between 2018 and 2019. Patients with incident hip fracture were included as our study population. We measured the longitudinal changes of the quality of life and daily activities function by using the EQ-5D-5L questionnaire and the Barthel Index of Activities of Daily Living, respectively. The assessment began at the index hospitalization, then continued at the following 7 points in time after discharge: 2 weeks, 1-, 2-, 4-, 6-, 9- and 12-month . We used the EQ-5D-5L Index Value Calculator version 2.0 to obtain the EQ-5D-5L index utility value. RESULTS : There are 72 patients included in this study. The mean age of our study population is 80 years old and 71% were women. The mean baseline T-score was -2.74 SD. The mean utility value was 0.285 at the index hospitalization. The mean of EQ5D-VAS score was 45.8 at the index hospitalization and generally increased to 55.5, 66.5, 70.2, 70.9, 79.9, 96.6 and 97.5 at the follow-up points in time. The mean score of Barthel Index was 28 at the index hospitalization and finally returned to 100 at the 9th month post discharge. CONCLUSIONS : The study showed the quality of life was extreme low at the time of acute hip fracture incidence, and improved steadily through one-year period post fracture. This information concerning local utility parameter was crucial for future economic evaluation of hip fracture related treatment in Taiwan.
Conference/Value in Health Info
2020-09, ISPOR Asia Pacific 2020, Seoul, South Korea
Value in Health Regional, Volume 22S (September 2020)
Code
PMS16
Topic
Clinical Outcomes, Patient-Centered Research
Topic Subcategory
Clinical Outcomes Assessment, Health State Utilities, Patient-reported Outcomes & Quality of Life Outcomes, Relating Intermediate to Long-term Outcomes
Disease
Diabetes/Endocrine/Metabolic Disorders, Geriatrics, Musculoskeletal Disorders
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