Author(s)
Hu KD1, Wu H2, Chow TS3, Sun W4, Huang XY5, Fan Q6, Wu YX3, Yin ZZ7, Li JN8, Ming WK1
1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2Jinan University, Guangzhou, China, 3International school, Jinan University, Guangzhou, China, 4Jinan U, GuangZhou, China, 5Jinan university, Guangzhou, 44, China, 6Peking Union Medical College Hospital, Beijing, China, 7Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, China, 8jinan u, guangzhou, China
OBJECTIVES : The prevalence of smoking in women younger than 40 years old has increased significantly in recent years. Though most of women who smoked before pregnancy are not likely to continue to smoke after they become pregnant, it has been proved that EuroQoL in ex-smokers is significantly lower than that in non-smokers. Moreover, they might develop smoke-related diseases due to previous smoking or suffer from smoke-related health consequences, which impaired their quality of life. METHODS : A national based cross-sectional study was conducted to determine the association between different smoking status and health-related quality of life (HRQoL) in pregnant women from diverse regions in China. A web-based questionnaire was asked during prenatal examination. HRQoL was measured through the EuroQoL five-dimension-five-level questionnaire and demographic data were collected. RESULTS : Totally 16,811 participants were included in this research. Significant difference in EQ-VAS scores were detected between non-smokers and ex-smoker (p<0.001) but there’s no significant difference between ex-smokers and smokers (p=0.247). In ex-smokers, proportion of pregnant women who suffer from health-related consequences in depression/anxiety dimension is much higher(p<0.001). Moreover, increased amounts of tobacco smoking before pregnancy could result in lower EQ-VAS and EQ-index (p=0.036 and p=0.005 respectively). CONCLUSIONS : Compared with non-smokers, ex-smokers in pregnant women had lower HRQoL. Also, it indicates that tobacco cessation during pregnancy did not improve HRQoL of ex-smokers apparently. Negative effects of smoking before pregnancy on HRQoL of pregnant women was in dose-response relationship. For women who smoked before being pregnant, they are more possible to suffer from health-related consequences in depression or anxiety. Tobacco smoking is becoming popular in young women and it is a severe health problem for their future pregnancy which was less addressed in the past. Government and clinicians are supposed to give more attention to ex-smokers in pregnancy and smokers in young women who intend to be pregnant.
Conference/Value in Health Info
2020-09, ISPOR Asia Pacific 2020, Seoul, South Korea
Value in Health Regional, Volume 22S (September 2020)
Code
PRS10
Topic
Epidemiology & Public Health, Patient-Centered Research
Topic Subcategory
Patient-reported Outcomes & Quality of Life Outcomes, Public Health
Disease
Mental Health, Reproductive and Sexual Health, Respiratory-Related Disorders
