VARIATIONS IN HEALTHCARE RESOURCE USE AND EXPENDITURES BY AGE IN PATIENTS UNDER AGE 65 NEWLY DIAGNOSED WITH PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIA (PSVT) IN THE UNITED STATES
Author(s)
Sacks N1, Everson KA2, Cyr PL3, Emden M3, Preib M3, Wood DR4, Pokorney SD5
1Tufts University School of Medicine, Boston, MA, USA, 2Precision Health Economics, Los Angeles, CA, USA, 3Precision Xtract, Boston, MA, USA, 4Milestone Pharmaceuticals, Inc., Saint-Laurent, QC, Canada, 5Duke University School of Medicine, Durham, NC, USA
Presentation Documents
OBJECTIVES : Characterize variations in downstream healthcare costs and catheter ablations in patients age <18y, 18-40y, and 41-64y newly diagnosed with Paroxysmal Supraventricular Tachycardia (PSVT). METHODS : Commercially insured patients from the Truven Health MarketScan® database with newly diagnosed PSVT (ICD-9: 427.0; ICD-10: I47.1) from January 1, 2011 to December 31, 2014 were included when observable three years before and after index diagnosis. Propensity matched controls were identified. Outcome measures included mean annual per-patient costs paid by insurers 3 years pre- and post-diagnosis, as well as ablations within 1 year post-diagnosis. RESULTS : The majority of the 13,092 newly diagnosed patients were age 41-64y (Age <18y: N=780; 6.0%; 18-40y: N=2,324; 17.8%; 41-64y: N=9,988; 72.3%) and female sex (Age <18y: 50.6% vs. 18-40y: 68.0%; vs. 41-64y: 62.5%). Costs in all age groups were relatively stable in the 13-36 months before index but rose significantly in the year immediately preceding diagnosis (P<0.0001). In the year immediately following diagnosis, costs more than tripled in patients age <18y (from $46,739 to $23,904; P<0.0001), and doubled in patients age 18-40y (from $10,203 to $20,127; P<0.0001) and 41-64y (from $11,796 to 23,543; P<0.0001) relative to the pre-diagnosis year. Costs for healthcare encounters with PSVT diagnoses accounted for more than two-thirds of these cost increases (Age <18y: 78.2%; 18-40y: 82.9%; age 41-64y: 68.2%). The proportion of patients treated with ablation in the year following PSVT diagnosis was highest in younger patients and decreased with age (Age <18y: 30.4% vs. 18-40y: 16.4% vs. 41-64y: 12.2%; P<0.0001). Matched control patients in all age groups had significantly lower costs throughout the study period (P<0.0001). CONCLUSIONS : Healthcare costs increased in the year immediately preceding PSVT diagnosis across all ages, consistent with the challenges in making a PSVT diagnosis. Cost increases following diagnosis may reflect costs of monitoring, ablation procedures, and medical management for PSVT.
Conference/Value in Health Info
2019-05, ISPOR 2019, New Orleans, LA, USA
Value in Health, Volume 22, Issue S1 (2019 May)
Acceptance Code
CV3
Topic
Economic Evaluation
Topic Subcategory
Cost/Cost of Illness/Resource Use Studies
Disease
Cardiovascular Disorders