TRENDS IN MORTALITY FROM LIP AND ORAL CAVITY CANCER IN COLOMBIA 2000 - 2024
Author(s)
Bruno Gutierrez, Ph.D.1, Nelson R. Alvis Zakzuk, Jr., MBA2, Nelson José Alvis Zakzuk, MSc3, Nelson Alvis-Guzman, MPH, PhD, MD4;
1Universidad del Valle, Cali, Colombia, 2ALZAK Foundation, Cartagena, Colombia, 3University of Sao Paulo, Sao Paulo, Brazil, 4Universidad de la Costa, Barranquilla, Colombia
1Universidad del Valle, Cali, Colombia, 2ALZAK Foundation, Cartagena, Colombia, 3University of Sao Paulo, Sao Paulo, Brazil, 4Universidad de la Costa, Barranquilla, Colombia
OBJECTIVES: To describe mortality trends from lip and oral cavity cancer. in Colombia 2000-2024
METHODS: This was an ecological time series study of lip and oral cavity cancer in Colombia between 2000 and 2024. ICD-10 codes C00 and C02-C06, were included. However, neoplasms of the base of the tongue (C01) and oropharynx were excluded due to their different anatomical classification and epidemiological profile. The distribution of causes by age, sex, and year was estimated. Proportional mortality rates (/100,000) were estimated. Trends in lip and oral cavity cancer mortality rate (OCMR) were analysed using Joinpoint regression to determine inflection points for temporal analysis and annual percent change (APC). Data were obtained from the national population statistics agency, DANE.
RESULTS: Between 2000 and 2024, there were 6,873 deaths (0.12% of the total) related to lip and oral cavity cancer. This was 50.9% in men and 64.1% in people aged over 65. The mean age at death was 69.1 years (SD: 15.1) (70.7 years (SD: 15.4) in women and 67.5 years (SD: 14.6) in men). 57.4% of deaths were from C02.9 (Malignant neoplasm of tongue, unspecified), 14.9% C06.9 (Malignant neoplasm of mouth, unspecified), and 9.4% C05.9 (Malignant neoplasm of the palate, unspecified). Between 2000 and 2024, OCMR increased from 0.50 (95% CI: 0.43-0.57) to 0.79 (95% CI: 0.72-0.87). In men, it increased from 0.50 (95% CI: 0.40-0.61) to 0.78 (95% CI: 0.68-0.89); in women, it increased from 0.49 (95% CI: 0.39-0.59) to 0.80 (95% CI: 0.69-0.81). The APC of the OCMR was 2.3716 (1.8899-2.8411); in men it was 2.0226 (1.391-2.6638), and in women it was 2.7568 (2.1346-3.3734). All increases were significant.
CONCLUSIONS: The mortality rate related to lip and oral cavity cancer increased significantly in Colombia during this period, with no gender differences observed.
METHODS: This was an ecological time series study of lip and oral cavity cancer in Colombia between 2000 and 2024. ICD-10 codes C00 and C02-C06, were included. However, neoplasms of the base of the tongue (C01) and oropharynx were excluded due to their different anatomical classification and epidemiological profile. The distribution of causes by age, sex, and year was estimated. Proportional mortality rates (/100,000) were estimated. Trends in lip and oral cavity cancer mortality rate (OCMR) were analysed using Joinpoint regression to determine inflection points for temporal analysis and annual percent change (APC). Data were obtained from the national population statistics agency, DANE.
RESULTS: Between 2000 and 2024, there were 6,873 deaths (0.12% of the total) related to lip and oral cavity cancer. This was 50.9% in men and 64.1% in people aged over 65. The mean age at death was 69.1 years (SD: 15.1) (70.7 years (SD: 15.4) in women and 67.5 years (SD: 14.6) in men). 57.4% of deaths were from C02.9 (Malignant neoplasm of tongue, unspecified), 14.9% C06.9 (Malignant neoplasm of mouth, unspecified), and 9.4% C05.9 (Malignant neoplasm of the palate, unspecified). Between 2000 and 2024, OCMR increased from 0.50 (95% CI: 0.43-0.57) to 0.79 (95% CI: 0.72-0.87). In men, it increased from 0.50 (95% CI: 0.40-0.61) to 0.78 (95% CI: 0.68-0.89); in women, it increased from 0.49 (95% CI: 0.39-0.59) to 0.80 (95% CI: 0.69-0.81). The APC of the OCMR was 2.3716 (1.8899-2.8411); in men it was 2.0226 (1.391-2.6638), and in women it was 2.7568 (2.1346-3.3734). All increases were significant.
CONCLUSIONS: The mortality rate related to lip and oral cavity cancer increased significantly in Colombia during this period, with no gender differences observed.
Conference/Value in Health Info
2026-05, ISPOR 2026, Philadelphia, PA, USA
Value in Health, Volume 29, Issue S6
Code
EPH147
Topic
Epidemiology & Public Health
Disease
SDC: Gastrointestinal Disorders