ECONOMIC IMPACT OF HYSTERECTOMIES AND POTENTIAL COST SAVINGS WITH HORMONAL IUD USE IN THE MANAGEMENT OF ABNORMAL UTERINE BLEEDING IN BRAZIL

Author(s)

JOSE MARIO ALVES JUNIOR, PhD, Ana Carolina Furian da Silva, MS, Nathalia Maria Mascarenhas Munhoes, MS, Indyanara Inacio Barreto, MS, Fatima Filomena Mafra Christoforo, PhD, Jose Emilio Duran Filomena Mafra Bueno, PhD.
UNIMED CAMPINAS, CAMPINAS, Brazil.
OBJECTIVES: To evaluate utilization trends, costs, and clinical profiles of hysterectomies compared with the use of levonorgestrel-releasing hormonal intrauterine devices (L-IUD 52 mg) among women with Abnormal Uterine Bleeding (AUB) in the Brazilian private healthcare system.
METHODS: Retrospective cohort including beneficiaries aged 40-50 years who underwent hysterectomy or insertion of a 52 mg L-IUD for AUB treatment between 2020 and October 2025. Administrative data were extracted from a large Brazilian Health Insurance Company (Unimed Campinas). Hysterectomy costs were analyzed according to surgical type. Budget impact models assessed scenarios of 30% and 50% reductions in hysterectomies when L-IUDs are used as the initial intervention.
RESULTS: The cohort included 260,950 women, with 3,479 hysterectomies (1.3%) and 6,489 L-IUD insertions (2.5%). Among L-IUD users, 77% had insertions performed in outpatient settings. Insertions increased through 2024 (108%), while hysterectomies increased by 50.7% during the period. The main diagnoses associated with hysterectomies were leiomyoma, endometriosis, and excessive menstruation. Average costs ranged from US$ 792,9 (partial open) to US$ 1.597,9 (partial laparoscopy). Cumulative spending was US$ 4.3 million on hysterectomies and US$ 1.5 million on L-IUDs. Only 6% of women undergoing hysterectomy had previously used an L-IUD, suggesting underutilization as a conservative therapy. In scenarios of 30%-50% reduction in surgeries through broader adoption of L-IUD, projected savings ranged from US$ 1 million to US$ 1.7 million over five years.
CONCLUSIONS: The L-IUD represents a less invasive, cost-effective therapeutic alternative with substantial potential to prevent high-cost surgical procedures. Expanding its use as a first-line therapy for AUB may support resource optimization and better alignment with value-based care models.

Conference/Value in Health Info

2026-05, ISPOR 2026, Philadelphia, PA, USA

Value in Health, Volume 29, Issue S6

Code

EE388

Topic

Economic Evaluation

Topic Subcategory

Budget Impact Analysis

Disease

No Additional Disease & Conditions/Specialized Treatment Areas, SDC: Reproductive & Sexual Health

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