CLINICAL EFFECTIVENESS OF 3D PRINTED ORTHOPAEDIC IMPLANTS COMPARED WITH CONVENTIONAL IMPLANTS: A SYSTEMATIC REVIEW AND METAANALYSIS

Author(s)

Pudi N. Seshu, Sr., PhD1, Kavita Kachroo, MBA, MHA, Other2, Jitendra Sharma, Ph.D2;
1Kalam Institute of Health Technology ( KIHT), Scientist-D, Visakhapatnam, India, 2Kalam Institute of Health Technology ( KIHT), Health Technology Assessement, Visakhapatnam, India
OBJECTIVES: Three-dimensional printing has revolutionized orthopaedics, evolving from anatomical models to patient-specific titanium implants. These devices improve surgical accuracy; in contrast to conventional implants such as PEEK, titanium produced through 3D printing provides enhanced osseointegration and stability. The objectives of this study were to analyze 3D bone implant evidence and to conduct a systematic review to determine the clinical effectiveness of 3D bone implants in patients requiring implantation with outcomes of operation time and intra operative fluoroscopies.
METHODS: A comprehensive search was performed at various electronic databases using PubMed, Web of Science, Google Scholar, and Cochrane. A PRISMA method is used to curate and collocate the studies. Quantitative data were pooled into statistical meta-analyses using the Cochrane Review Manager (RevMan) to compare clinical effectiveness of 3D bone implants with conventional implants.
RESULTS: A total of 3598 articles were obtained, and after evaluation, 110 articles were accepted that answered the research questions and met the criteria for systematic review and meta-analysis. Therefore, the outcomes of the meta-analysis are the pooled analysis for operation time with mean difference (MD) = -23.30 minutes (95% CI -26.97 to -19.63). and other outcome intraoperative fluoroscopies pooled analysis with (MD) = -3.16 (95% CI: -4.07 to -2.25), thus showing a statistically significant effect favouring with 3D bone implants
CONCLUSIONS: In this review we found that 3D bone implants played an important role in decreasing operation time on average, about 23 minutes, and also intraoperative fluoroscopies showed reduction and improved surgical precision and preoperative planning, reducing the need for repeated intraoperative imaging. Therefore, this review hypothesizes 3D-printed orthopedic implants present distinct advantages over conventional implants, such as enhanced safety, efficiency and surgical accuracy.

Conference/Value in Health Info

2026-05, ISPOR 2026, Philadelphia, PA, USA

Value in Health, Volume 29, Issue S6

Code

HTA61

Topic

Health Technology Assessment

Disease

SDC: Musculoskeletal Disorders (Arthritis, Bone Disorders, Osteoporosis, Other Musculoskeletal)

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