THE STROKE IMPACT SCALE 3.0: VALIDITY AND RELIABILITY EVALUATION OF THE VIETNAMESE VERSION

Author(s)

Hien T. Pham, MSc1, Doan T. Duong, MSc2, Nguyen T. Tran, MSc2, Yen T. Nguyen, PhD2, Nga T. Nguyen, MD1, Thanh D. Le, PhD1;
1Thong Nhat Hospital, Ho Chi Minh, Viet Nam, 2University of Medicine and Pharmacy at Ho Chi Minh city, Ho Chi Minh, Viet Nam
OBJECTIVES: Stroke causes a range of physical disabilities, emotional changes. Focusing on patient-reported outcomes, specifically health-related quality of life (HRQoL) as a target outcome for clinical decisions is therefore more important. The Stroke Impact Scale version 3.0 (SIS 3.0) is a widely for assessing HRQoL in stroke patients. Although, the Vietnamese translated version is available, its psychometric properties have not been validated. This study aimed to evaluate validity of the Vietnamese version of the SIS 3.0.
METHODS: We conducted a cross-sectional study including adult patients (≥18 years), were hospitalized due to stroke (ICD-10: I61-I69) at Thong Nhat Hospital from 04/2024 to 07/2024. The SIS 3.0 comprises 59 items across eight domains, each item is rated on a 5-point Likert scale and standardized to 0-100. The Vietnamese SIS 3.0 was used with a permission from Mapi Research Trust. Internal consistency reliability was assessed using Cronbach’s alpha (≥0.70), with all item-total correlations >0.30. Convergent validity was examined by assessing correlations between SIS 3.0 domain scores and the EQ-5D-5L index.
RESULTS: We interviewed a total of 80 patients, with the mean age of 66.65 (SD = 14.58) years and 51.3% male. Most patients had ischemic stroke (87.5%), with hypertension (71.3%) and diabetes (38.8%). The instrument demonstrated high internal consistency across domains, with Cronbach’s alpha ranging from 0.859 to 0.983. All items showed acceptable item-total correlations, exceeding the recommended threshold of 0.30. Strong correlations were observed between the total SIS score and EQ-5D-5L index (r=0.718, p < 0.01), and between the SIS physical domain and EQ-5D-5L domain (r=0.743, p < 0.01). The correlations between hand function, emotional factors, and EQ-5D-5L did not reach statistical significance (p > 0.05).
CONCLUSIONS: These findings suggest that the Vietnamese version of the SIS 3.0 demonstrates strong internal consistency, convergent validity. The reliability of the instrument need to be evaluated in future research.

Conference/Value in Health Info

2026-05, ISPOR 2026, Philadelphia, PA, USA

Value in Health, Volume 29, Issue S6

Code

PCR80

Topic

Patient-Centered Research

Topic Subcategory

Instrument Development, Validation, & Translation

Disease

SDC: Cardiovascular Disorders (including MI, Stroke, Circulatory)

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