A POPULATION-BASED EPIDEMIOLOGICAL ANALYSIS WITH PROJECTIONS OF FETAL AND NEONATAL TRANSIENT METABOLIC DISORDERS IN HUNGARY
Author(s)
Tímea Csákvári, MSc, PhD1, Diána Elmer, BSc, MSc, PhD2, Krisztina Palkovics, MSc1, Luca F. Kajos, BSc, MSc, PhD2, Kálmán Kovács, PhD3, József Bódis, PhD, DSc, Med.H3, Imre Boncz, MSc, PhD, MD2;
1University of Pécs, Faculty of Health Sciences, Institute for Health Insurance, Zalaegerszeg, Hungary, 2University of Pécs, Faculty of Health Sciences, Institute for Health Insurance, Pécs, Hungary, 3University of Pécs, Clinical Centre, Department of Obstetrics and Gynaecology, Pécs, Hungary
1University of Pécs, Faculty of Health Sciences, Institute for Health Insurance, Zalaegerszeg, Hungary, 2University of Pécs, Faculty of Health Sciences, Institute for Health Insurance, Pécs, Hungary, 3University of Pécs, Clinical Centre, Department of Obstetrics and Gynaecology, Pécs, Hungary
OBJECTIVES: Diabetes in pregnancy represents a significant public health concern with established impacts on fetal health outcomes. Our aim was to evaluate the epidemiology of specific fetal and neonatal transient metabolic disorders (FNTMD) in Hungary, as well as to project future trends between 2010 and 2035.
METHODS: A retrospective study was conducted using nationwide real-world data from the Hungarian ’Pulvita’ Health Data Warehouse. ICD-10 codes P70.0-P70.9 were used to identify patients in outpatient and inpatient care. Annual patient numbers, the number of hospital days, the number of FNTMD patients per 1,000 live births were analyzed with different forecasting models to project future prevalence up to 2035, using SPSS 27.0.
RESULTS: In 2010, the number of FNTMD inpatients per 1,000 live births was 102.68, increasing to 141.30 by 2024. Within this patient population, cases diagnosed as syndromes of infants of mothers with GDM more than doubled, rising from 24.91 to 63.34 per 1,000 live births. Overall, the time series reached its maximum in 2022, at 147.42 per 1,000 live births. The reduction in mean length of hospital stay (M2010=6.94 days; M2024=5.24 days) indicates improvements in care delivery. In outpatient care, annual patient numbers per 1,000 live births ranged from a minimum of 8.93 in 2015 to a peak of 13.09 in 2012. Projections to 2035 indicate overall stability in absolute case numbers, with a modest increase anticipated in inpatient care.
CONCLUSIONS: The number of FNTMD cases is not expected to decrease significantly; inpatient data indicate an upward trend, while outpatient care is anticipated to remain stable. The results may inform national-level health care planning by improving the anticipation of future service demands in neonatal care.
METHODS: A retrospective study was conducted using nationwide real-world data from the Hungarian ’Pulvita’ Health Data Warehouse. ICD-10 codes P70.0-P70.9 were used to identify patients in outpatient and inpatient care. Annual patient numbers, the number of hospital days, the number of FNTMD patients per 1,000 live births were analyzed with different forecasting models to project future prevalence up to 2035, using SPSS 27.0.
RESULTS: In 2010, the number of FNTMD inpatients per 1,000 live births was 102.68, increasing to 141.30 by 2024. Within this patient population, cases diagnosed as syndromes of infants of mothers with GDM more than doubled, rising from 24.91 to 63.34 per 1,000 live births. Overall, the time series reached its maximum in 2022, at 147.42 per 1,000 live births. The reduction in mean length of hospital stay (M2010=6.94 days; M2024=5.24 days) indicates improvements in care delivery. In outpatient care, annual patient numbers per 1,000 live births ranged from a minimum of 8.93 in 2015 to a peak of 13.09 in 2012. Projections to 2035 indicate overall stability in absolute case numbers, with a modest increase anticipated in inpatient care.
CONCLUSIONS: The number of FNTMD cases is not expected to decrease significantly; inpatient data indicate an upward trend, while outpatient care is anticipated to remain stable. The results may inform national-level health care planning by improving the anticipation of future service demands in neonatal care.
Conference/Value in Health Info
2026-05, ISPOR 2026, Philadelphia, PA, USA
Value in Health, Volume 29, Issue S6
Code
EPH92
Topic
Epidemiology & Public Health
Topic Subcategory
Public Health
Disease
SDC: Diabetes/Endocrine/Metabolic Disorders (including obesity)