ASSOCIATION OF MARIJUANA USE AND HEALTH-RELATED QUALITY OF LIFE AMONG CARDIOVASCULAR DISEASE PATIENTS. EVIDENCE FROM THE BEHAVIORAL RISK FACTOR SURVEILLANCE SYSTEM
Author(s)
Batool Khattab, MPH1, Laura Elisabeth Gressler, MS, PhD2, Corneliu Bolbocean, PhD3.
1PhD student, University of Arkansas for Medical Sciences (UAMS), Little Rock, AR, USA, 2UAMS College of Pharmacy, Little Rock, AR, USA, 3University of Oxford, Oxford,, United Kingdom.
1PhD student, University of Arkansas for Medical Sciences (UAMS), Little Rock, AR, USA, 2UAMS College of Pharmacy, Little Rock, AR, USA, 3University of Oxford, Oxford,, United Kingdom.
Presentation Documents
OBJECTIVES: Marijuana use is increasingly prevalent in the United States. However, its impact on health-related quality of life (HRQoL) among individuals with cardiovascular disease (CVD) remains unclear. This study examined the association between marijuana use and HRQoL among adults with CVD, using the 2023 Behavioral Risk Factor Surveillance System (BRFSS) survey.
METHODS: Adults (>18 years) with self-reported CVD residing in states that administered the marijuana optional module were included. Marijuana use (past-month non-user/current user) and route of administration were evaluated in relation to HRQoL outcomes, including EQ-5D index and EQ visual analog scale (VAS) scores, self-rated general health, days with poor mental, physical health, and activity limitations. Multivariate Tobit, logistic, and ordinal regression models were used to test these associations, adjusting for demographic and clinical covariates, and accounting for complex survey design. Secondary analyses were stratified by age group.
RESULTS: Current marijuana use was associated with significantly lower EQ VAS scores (-2.67, 95% CI: -5.18, -0.17) and higher odds of reporting poor mental health days (OR: 1.59, 95% CI: 1.17, 2.16). Ingested marijuana was associated with lower EQ VAS scores and poorer mental health, while vaping was associated with higher odds of fair/poor general health but lower odds of activity limitation. Age-stratified analyses indicated these associations mainly in younger adults, where marijuana use was associated with significantly lower EQ-5D index (-0.035, 95% CI: -0.069, -0.00031), lower EQ VAS score (-4.46, 95% CI: -8.10, -0.82), and higher odds of poor mental health (OR 1.70, 95% CI: 1.11, 2.6). Among older adults, marijuana use was associated with lower odds of fair/poor general health (OR 0.57, 95% CI: 0.39, 0.83).
CONCLUSIONS: Among adults with CVD, particularly younger adults, marijuana use was associated with poorer HRQoL and mental health. These findings support the need for age-targeted screening and counseling regarding marijuana use in CVD patients.
METHODS: Adults (>18 years) with self-reported CVD residing in states that administered the marijuana optional module were included. Marijuana use (past-month non-user/current user) and route of administration were evaluated in relation to HRQoL outcomes, including EQ-5D index and EQ visual analog scale (VAS) scores, self-rated general health, days with poor mental, physical health, and activity limitations. Multivariate Tobit, logistic, and ordinal regression models were used to test these associations, adjusting for demographic and clinical covariates, and accounting for complex survey design. Secondary analyses were stratified by age group.
RESULTS: Current marijuana use was associated with significantly lower EQ VAS scores (-2.67, 95% CI: -5.18, -0.17) and higher odds of reporting poor mental health days (OR: 1.59, 95% CI: 1.17, 2.16). Ingested marijuana was associated with lower EQ VAS scores and poorer mental health, while vaping was associated with higher odds of fair/poor general health but lower odds of activity limitation. Age-stratified analyses indicated these associations mainly in younger adults, where marijuana use was associated with significantly lower EQ-5D index (-0.035, 95% CI: -0.069, -0.00031), lower EQ VAS score (-4.46, 95% CI: -8.10, -0.82), and higher odds of poor mental health (OR 1.70, 95% CI: 1.11, 2.6). Among older adults, marijuana use was associated with lower odds of fair/poor general health (OR 0.57, 95% CI: 0.39, 0.83).
CONCLUSIONS: Among adults with CVD, particularly younger adults, marijuana use was associated with poorer HRQoL and mental health. These findings support the need for age-targeted screening and counseling regarding marijuana use in CVD patients.
Conference/Value in Health Info
2026-05, ISPOR 2026, Philadelphia, PA, USA
Value in Health, Volume 29, Issue S6
Code
PCR42
Topic
Patient-Centered Research
Topic Subcategory
Health State Utilities, Patient-reported Outcomes & Quality of Life Outcomes
Disease
SDC: Cardiovascular Disorders (including MI, Stroke, Circulatory)