Published Jan 2017
Wailoo AJ, Hernandez-Alava M, Manca A, et al. Mapping to Estimate Health-State Utility from Non–Preference-Based Outcome Measures: An ISPOR Good Practices for Outcomes Research Task Force Report. Value Health 2017; 20(1):18-27.
Economic evaluation conducted in terms of cost per quality-adjusted
life-year (QALY) provides information that decision makers find useful
in many parts of the world. Ideally, clinical studies designed to assess
the effectiveness of health technologies would include outcome measures
that are directly linked to health utility to calculate QALYs. Often
this does not happen, and even when it does, clinical studies may be
insufficient for a cost-utility assessment. Mapping can solve this problem.
It uses an additional data set to estimate the relationship between
outcomes measured in clinical studies and health utility. This bridges
the evidence gap between available evidence on the effect of a health
technology in one metric and the requirement for decision makers to
express it in a different one (QALYs). In 2014, ISPOR established a Good
Practices for Outcome Research Task Force for mapping studies. This
task force report provides recommendations to analysts undertaking
mapping studies, those that use the results in cost-utility analysis, and
those that need to critically review such studies. The recommendations
cover all areas of mapping practice: the selection of data sets for the
mapping estimation, model selection and performance assessment,
reporting standards, and the use of results including the appropriate
reflection of variability and uncertainty. This report is unique because it
takes an international perspective, is comprehensive in its coverage of
the aspects of mapping practice, and reflects the current state of the art.
Keywords: economic evaluation, health utility, mapping, quality of life.
Copyright © 2017, International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc.