Session (CTI)

MFN is reshaping how companies prioritize launch markets, with 19 markets currently included across the GENEROUS, GLOBE, and GUARD programs. While these “non-3G” markets may represent opportunities for earlier launches following the US, their health systems continue to face significant budget constraints driven by macroeconomic pressures, including inflation, currency devaluation, and geopolitical instability. This cross-regional forum will examine the opportunities and risks created by this evolving pricing environment across Latin America, the Middle East, and Asia, including the potential implications for access in neighboring lower-income markets. OVERVIEW Presented by the ISPOR Latin America Consortium, ISPOR Asia Pacific Consortium, and ISPOR Arab Network, this forum evaluates three regional realities covering four markets: • LATAM (G20 UMICs, near-to-cross to HIC): Argentina and Mexico. • GCC (HIC, part of the GCC bloc's joint negotiations and reference pricing): UAE. • AP (LMIC yet the world's 3rd largest pharma market): India. Panelists representing each network's leadership will debate three cross-regional pressures: 1. Macroeconomic Headwinds: The conflict between rigid GNI-per-capita graduation metrics and the fiscal reality of health systems enduring hyperinflation, war, or currency devaluation. 2. Pooled Procurement: How high-income pricing demands clash with consolidated buying blocs, such as joint GCC negotiations and reference pricing or PAHO Regional Revolving Funds in Latin America. 3. Neighboring Country Impact: The operational risk to lower-priced neighboring countries that border a non-3G market, where high commercial prices set in the bordering UMIC or HIC destabilize affordability and access in the adjacent, lower-price country.