Session (CTI)

As HTA and Joint Clinical Assessment (JCA) requirements continue to evolve, decision-makers increasingly rely on evidence beyond direct head-to-head clinical trials. This session showcases the application of matching-adjusted indirect comparisons (MAICs), network meta-analysis (NMA), real-world evidence (RWE), and surrogate endpoint validation to address evidence gaps and support robust comparative effectiveness assessments. Presentations highlight methodological innovations and practical approaches for generating decision-ready evidence in areas where traditional clinical trial data alone may be insufficient.