Session (CTI)

Selection of the most appropriate method to capture patient treatment preferences is fundamental to support the consideration of patient priorities in decisions across the medical product lifecycle (MPLC). The discrete choice experiment (DCE) is the most commonly applied method in health but its application is often limited by the comparatively large sample size required. However, whilst extensive guidance and many training resources are available on DCEs, there are few resources to support the selection of non-DCE methods alongside DCEs. This workshop aims to provide insights on the selection of preference elicitation methods to inform decisions along the MPLC, the extent to which different methods address different research objectives, and when to consider the use of non-DCE methods. Jennifer Whitty will provide an introduction to preference elicitation method selection, poll the audience on their knowledge of DCE and non-DCE methods and moderate the workshop. Michael Bui will present evidence from a systematic review suggesting suboptimal selection of preference elicitation methods across some studies. Jorien Veldwijk will present methods identified as promising to elicit preferences for MPLC decision making, highlighting their application and gaps in existing guidance. She will discuss the outcomes of a study among MPLC stakeholders about importance of different method’s characteristics for decision-making. Francesco Pignatti will focus on method selection for research questions to inform regulatory decisions, drawing from experience with submission of preference studies to support the evaluation of new drug applications to the European Medicines Agency. Audience feedback will be sought (via poll and interactive discussion) on method selection across the MPLC to inform public consultation around the forthcoming ICH E22 guidance on Considerations for Patient Preference Studies.