OBJECTIVES: Diabetes mellitus is a chronic disease and if it is not treated properly it can cause various complications in patients. To improve the quality of life of the patients with diabetes mellitus needs the appropriate interventions from health care providers. The aim of this study was to measure the effect of pharmacist intervention on patient reported quality of life on all domains of EQ-5D.

METHODS: This randomized controlled study is carried out in different hospitals of Malaysia to evaluate the impact of a pharmacist intervention on patient reported quality of life when there HbA1c is controlled by pharmacist interventions. A generic HRQoL tool EQ-5D was used to report the data. To identify the problems in individual EQ-5D domains and (VAS) mean scores ANCOVA and Logistic regression was used.

RESULTS: The average HbA1c values decreased from 10.15±1.42 to 8.21±0.75 in the intervention group (p<0.05). The intervention group showed an improvement in the quality of life domains. Mobility domain decrease from 3.21±0.25 to 2.21±0.45 (p<0.013), Self-care domain decrease from 4.11±0.75 to 3.291±0.85 (p<0.045), Usual activity domain decrease from 2.81±0.65 to 2.29±0.85 (p<0.655), Pain/ Discomfort domain decrease from 3.19±0.34 to 2.91±0.65 (p<0.065), Anxiety/ Depression domain decrease from 3.51±0.25 to 2.21±0.45 (p<0.015) and the VAS mean score is improved from 55.59±8 to 65.62±9 (p<0.005)

CONCLUSIONS: Patients features were significantly related with the HRQoL in type 2 diabetes. The significant and positive improvement was seen among the different domains of EQ-5D with the intervention of pharmacist. With the intervention of pharmacist not only the HbA1c improves but also the all health related domains also improved in patients.