OBJECTIVES: The purpose of the study is to compare results of Conjoint analysis from 3 studies in ophthalmology with other standard measures of QoL. METHODS: The 3 choice based conjoint (CBC) studies included two in people with glaucoma (N=109, N=74) in which the same attributes but a different presentation order was used, and one in people with Age Related Macular Degeneration (N= 126). Other QoL measures included time trade off, VF-14, NEI-VFQ 25 and EuroQoL. RESULTS: In all 3 studies the top two attributes were ‘reading' and ‘getting about outside'. For the two glaucoma studies, lower ranked attributes changed position under different presentational order. A simpler version of the conjoint task using only 3 of the 5 attributes was given to selected AMD patients with poor vision and showed the same rank order of attributes as in the 5 attribute task. There were very low correlations between individual conjoint measures and other Qol measures. (e.g. only 2 out of 65 intercorrelations between NEI and conjoint scores reached p<0.05). In time trade off, only around 50% of AMD patients and 20% of glaucoma patients were prepared to trade any remaining years and in both cases it was those with poorer vision (Snellen acuity > 6/12) who were willing to trade (p<0.01). All studies showed two subgroups of patients with priorities in ‘reading' and ‘getting about outdoors'. Shifts of attribute preference for changing levels of visual acuity and visual field occurred but not changes in rank order. CONCLUSION: Results from 3 studies (2 glaucoma, 1 ARMD) show little relationship between Conjoint QoL measures and TTO, VF-14, NEI-VFQ 25 and EuroQoL suggesting they are assessing different aspects of QoL.