Psoriasis is a chronicle disease, which concerns 4.7% of the French population. Although it does not shorten life it has major consequences on patients' daily life because of the damage to the body image. OBJECTIVE: The purpose of this study is to report preliminary findings of perceived disability in patients with psoriasis. METHOD: SPOT is a longitudinal, prospective, observational, programme. 2000 patients with mild to moderate psoriasis, will be recruited. (1000 Chronic Psoriasis Patient & 1000 New Psoriasis Patient). The Psoriasis Disability Index [PDI] (Finlay AY et al 1987) and the SF 12 are evaluated every 3 months. RESULTS: The preliminary results concern the analysis of the first 413 PDI scales completed at the inclusion visit. The mean PDI score of the chronic psoriasis patients (CPP) (n=215) was 15,2 (sd13,2) and the mean PDI score of the new psoriasis patients (NPP) (n=198) was 10,4 (sd11,7) (p<0.0001). When the sub-group of retired and housewife patients was analysed there was no difference in the scores between the CPP and NPP. However, the sub-group consisting of salaried employees, unemployed and sick leave patients showed a clear difference, mean PDI of CPP 14,4 (n=149) compared to NPP mean PDI=9,7 (n=158) (p=0.0003). When all questionnaires were analysed the "active population" are less disabled than the "inactive group" (p<0.05) and this difference is also seen within the NPP (p<0.05). CONCLUSION: This first analysis demonstrates the disability experienced by CPP and its greater impact on the "active population". This study will enable long-term monitoring of the evolution of patients' psoriasis and the perception of patients concerning their management.