BURDEN OF ILLNESS SURVEY IN PATIENTS WITH PAINFUL NEUROPATHIC DISORDER (PNDS) IN GERMANY.

Author(s)

Tölle TR1, Stridde E2, 1 Technische Universität München, München, Germany; 2 Pfizer GmbH, Karlsruhe, Germany

OBJECTIVES: Aim of the survey was: 1) to identify characteristics of patients with PND's 2) to quantify burden of health resource utilisation among this patients 3) to investigate the impact of PND's and its treatment on productivity and daily functioning. METHODS: In this cross-sectional, one-time survey we focused on the documentation of self-reported functioning and well-being, pain exerience, MD's reported medication use, productivity and employment status. Well established questionaires / scals were used for data collection. RESULTS: A total of 202 patient questionnaires were eligible for data-analysis. Diabetic (n = 62) and Postherpetic (n = 33) neuropatic pain were most prominent where 86% of the patients reported their worst pain within the last 24 hours as moderate 33% or severe 53% (all indications). The pain severity index results where nearly similar but moderate was reported mostly (57%). EQ-5D-scores was comparable for worst pain within the last 24 hours and pain severity index and was low in patients reporting “severe pain experience” (0.3/0.13). Ten percent (10%) of patients were early retired, 12% were disabled due to neuropatic pain, 17% had to reduce scheduled work and 27% of the patients reported a sustantial reduction in work productivity because of their NeP. Analgesics (77%) were prescribed most commonly followed by antiepileptics (53%), antidepressants (37%) and Hypnotics (30%). Combination is common. Patient satisfaction by using the prescribed medication was high. In total, 21% were “extremely satisfied” and 55% were “somewhat satisfied”. CONCLUSIONS: Treatment of NeP should be optimized since a high percentage of patients reported a considerable pain within 24h. However, it is astonishing that in general patients satisfaction with their current treatment was high. The mismatch between treatment quality and patient satisfaction is open to debate. Further investigations regarding the alternative “coping strategies” beyond pharmacological treatment are needed.

Conference/Value in Health Info

2004-10, ISPOR Europe 2004, Hamburg, Germany

Value in Health, Vol. 7, No. 6 (November/December 2004)

Code

PPN6

Topic

Economic Evaluation

Topic Subcategory

Cost/Cost of Illness/Resource Use Studies

Disease

Systemic Disorders/Conditions

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