INTENSITY OF CARE IN ECONOMIC EVALUATIONS OF CHRONIC HYPERTENSION
Author(s)
Krista Payne, MEd, Director, HECON Study Design and Data Capture1, William Daley, MD, Executive Director, Cardiovascular and Metabolism2, Zeba M Khan, PhD, Head, Health Economics & Pricing Strategy3, K Jack Ishak, PhD, Biostatistician1, John M. Flack, MD, MPH, Interim Chairman4, Eric Jose Velázquez, MD, Assistant Professor of Medicine5, Shawna D Nesbitt, MDMS, Associate Professor6, Karen Stark, RNBSN, Senior Clinical Research Scientist2, J. Jaime Caro, MDCM, FRCPC, FAC, President & Scientific Director7, Robert Califf, MD, Vice Chancellor for Clinical Research and Director, Duke International Medicine Institute51Caro Research Institute, Montreal, QC, Canada; 2 Novartis Pharmaceuticals Corporation, Florham Park, NJ, USA; 3 Novartis Pharma AG, Basel, Switzerland; 4 Wayne State University, Detroit, MI, USA; 5 Duke University Medical Center, Durham, NC, USA; 6 University of Texas Southwestern Medical Center, Dallas, TX, USA; 7 Caro Research Institute, Concord, MA, USA
OBJECTIVES: Economic evaluations typically assume a constant intensity of care (e.g., one visit/cycle). The tenability of this assumption was examined using data from BPSZ- BLISS, a naturalistic study that collects demographics, blood pressure, and other outcomes in “usual care” patients from the US, including Puerto Rico. METHODS: Baseline, age, gender, ethnicity and blood pressures were recorded. Charts of subjects with chronic hypertension were reviewed for: date of diagnosis, date of the most recent visit, and blood pressures. The time between most recent and baseline visits was examined as a marker of intensity of care. Differences in times were also compared by ethnicity. RESULTS: In 8,023 subjects, 5,882 (73%) had chronic hypertension (53.0% female, 69.7% Caucasian, 22.5% Black, 4.6% Hispanic, 3.1% other). Mean BP at most recent visit was 147.7 mmHg systolic, 88.0 mmHg diastolic. There was a broad range of times between most recent and baseline visits (mean 112 days SD: 225). Older patients, females, those with prior cardiovascular disease and those hypertensive at MRP visit had shorter times. Visits tended to be sooner for Caucasian patients: 105 days (SD: 185 days); only Blacks were seen significantly later (24 days 95% CI: 11 - 38); Hispanic patients (19 days, 95% CI: -10 - 49); others (31 days, 95% CI: -4 - 65). The difference between Black and Caucasian patients persisted after controlling for potential differences in hypertensive status at the follow-up visits, age, sex and history of cardiovascular disease. CONCLUSION: Visit frequency varies widely and is influenced by clinical and demographic characteristics. This should be taken into account in economic evaluations, as well as the impact on health outcomes.
Conference/Value in Health Info
2007-09, ISPOR Latin America 2007, Cartagena, Colombia
Value in Health, Vol. 10, No. 6 (November/December 2007)
Code
PCV4
Topic
Economic Evaluation
Topic Subcategory
Cost/Cost of Illness/Resource Use Studies
Disease
Cardiovascular Disorders
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