UTILIZATION OF ACE INHIBITORS IN CONGESTIVE HEART FAILURE AMONG ELDERLY IN QUEBEC

Author(s)

LeLorier J, Couture J, Blais L, Castilloux A-M, Centre de recherche, Centre hospitalier de l’Université de Montréal, Campus Hôtel-Dieu, Quebec, Canada

BACKGROUND: In 1991, SOLVD demonstrated a decrease in hospitalization and mortality rates by using angiotensin converting enzyme inhibitors (ACEI) in chronic congestive heart failure (CHF). METHODS: We conducted a study on a 10% random sample of subjects aged 65 years and older from the universal health insurance plan in Quebec. We studied all the elderly who had a dispensation of digoxin ? 0,125 mg/d and furosemide?? 40 mg/d (DF) from September 1991 to December 1994. RESULTS: Among 3,565 subjects, 61.7% used an ACEI at least once after the first dispensation of DF. Visiting a cardiologist was the strongest predictor of an ACEI dispensation (OR 1.58 95% CI 1.44-1.74). The use of ACEI remained stable from 1991 to 1994 (p = 0.92). In a subgroup of subjects free of ACEI and of any combination of digoxin/furosemide one year prior to the first DF dispensation (incident cases), 51.7% had at least one dispensation of an ACEI following the first dispensation of DF. Among these incident users of DF, 79.3% began the ACEI in the 3 months following the first dispensation of DF. CONCLUSION: In elderly taking digoxin and furosemide, the use of ACEI is widespread. Since the publication of SOLVD in 1991, there has been no change in the utilization of ACEI over time.

Conference/Value in Health Info

1998-12, ISPOR Europe 1998, Cologne, Germany

Value in Health, Vol. 2, No. 1 (January/February 1999)

Code

CV3

Topic

Health Service Delivery & Process of Care

Topic Subcategory

Prescribing Behavior

Disease

Cardiovascular Disorders

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