OBJECTIVES: To determine rate of adoption of saliva concentrations as a monitoring method for antiepileptic drugs (AEDs). To determine whether child neurologists would prefer saliva testing to serum testing to obtain AED concentrations for clinical practice. METHODS: A survey asked participants about use, availability, and value to the physician of saliva AED concentrations. Respondents chose between the following four responses when considering value: 1) Very valuable, willing to spend 1/2 hour of time per patient to arrange; 2) Moderately valuable, willing to spend 10 minutes of time per patient to arrange; 3) Not very valuable, might use test but would not spend extra time to arrange; and 4) Of no special value, I doubt that I would use such a test. All members of the Child Neurology Society were surveyed. Surveys were re-mailed to non-responders after one- and two-month intervals. RESULTS: We mailed 1006 surveys and received 546 responses (54%) and 57 surveys were returned undelivered. Less than 1% of respondents had obtained a saliva AED concentration in the last year. Seven percent stated there was an available laboratory to perform saliva AED concentration determinations. Fifty-three percent of individuals indicated that having a pain-free method of AED concentration determination was very or moderately valuable to them and 68% stated that the ability to obtain real-time samples outside of the clinical environment was very or moderately valuable. CONCLUSIONS: Most child neurologists have not obtained saliva AED concentrations and perceive they do not have this technology available to them. The majority of respondents would be willing to spend 10-30 minutes of time to arrange for saliva AED concentrations to prevent patient discomfort and obtain real-time concentrations.