Author(s)
Poliakova K1, Fisun A2, Klabukova D2, Ermolaeva T2, Davydovskaya M2, Kokushkin K3
1State Budgetary Institution of Moscow City “Clinical Trials and Healthcare Technology Assessment Scientific-Research Centre of Moscow Department of Healthcare”, Moscow, MOW, Russia, 2State Budgetary Institution of Moscow City “Clinical Trials and Healthcare Technology Assessment Scientific-Research Centre of Moscow Department of Healthcare”, Moscow, Russian Federation, 3State Budgetary Institution of Moscow City “Clinical Trials and Healthcare Technology Assessment Scientific-Research Centre of Moscow Department of Healthcare”, Moscow, Russia
OBJECTIVES: Active case detection and early detection are essential principles of mortality reduction among cancer patients. The aim of the study was to analyze patient detection with first diagnosed malignant neoplasms (excluding leukemia, ICD-10 C91-C95) in Moscow. METHODS: An analytical model was constructed with the application of correlation analysis, taking into account the data of Russian Federal State Statistics Service (Rosstat) for 2017, as well as literature sources. RESULTS: There was estimated that the lowest percentage of active detection among new cancer patients accrue to: pharyngeal cancer (PhC)– 1,86%; pancreatic cancer (PC)– 3,17%; liver and intrahepatic bile duct cancer (LC)– 4,97%; esophageal cancer (EC) – 5,26%; malignant lymphoma (ML) (C81-C85, C88, C90, C96) – 5,81%. Depending on the stage of the tumor process, these types of malignant neoplasms were broken down as follows: PhC stages I – 1,42%, IV – 70,17%; PC stages I – 5,28%, IV – 60,43%; LC stages I – 5,49%, IV – 55,79%; EC stages I – 7,02%, IV – 37,77%; ML stages I – 5,75%, IV – 10,10%. Using correlation analysis, the following results were obtained: strong positive correlation between active patient detection and patient detection that first diagnosed on stage I (r=0,73;p≤0,001); strong negative correlation between active patient detection and patient detection first diagnosed on stage IV (r=-0,75;p≤0,001); strong negative correlation between patient detection first diagnosed on stage I and patient mortality (r=-0,77;p≤0,001); strong positive correlation between patient detection first diagnosed on stage IV and patient mortality (r=0,86;p≤0,001). Correlation between active patient detection and patient detection first diagnosed on stage II and stage III was week. CONCLUSIONS: The structure of patient detection with first diagnosed malignant neoplasms in Moscow shows that early detection and diagnosis are crucially important, as there is a strong correlation between active patient detection, cancer stage and patient mortality.
Conference/Value in Health Info
2018-11, ISPOR Europe 2018, Barcelona, Spain
Value in Health, Vol. 21, S3 (October 2018)
Code
PRM250
Topic
Methodological & Statistical Research
Topic Subcategory
Confounding, Selection Bias Correction, Causal Inference
Disease
Oncology