LINE OF THERAPY (LOT) DEFINITION IMPACTS SECOND-LINE (2L) SURVIVAL DURATION IN A METASTATIC PANCREATIC CANCER (MPCA) ELECTRONIC HEALTH RECORD DATABASE
Author(s)
Fish S, Flick ED, Swern A, Tu N, Jiang R, Jirau-Lucca G, Ondovik MS, Huang JH, Louis CU
Celgene Corporation, Summit, NJ, USA
OBJECTIVES: Real-world data analyses generally use treatment(tx) start and stop dates to define LOT; however, when an electronic health record(EHR) database captures the date of disease progression(PD), this can be used to enhance the definition of LOT. We explored the impact that this has on 2L survival outcomes. METHODS: A retrospective analysis of mPCa patients(pts) treated in US community practice settings was conducted utilizing the Flatiron Health EHR-derived database. Two algorithms were applied to define LOT: tx change or > RESULTS:
Conference/Value in Health Info
2018-11, ISPOR Europe 2018, Barcelona, Spain
Value in Health, Vol. 21, S3 (October 2018)
Code
PRM30
Topic
Clinical Outcomes, Methodological & Statistical Research
Topic Subcategory
Clinical Outcomes Assessment, Confounding, Selection Bias Correction, Causal Inference
Disease
Oncology
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