OBJECTIVES: to assess feasibility, convergent validity and reliability of the Italian version of the Infants' Dermatitis Quality Of Life Index (IDQOL) and the Family Dermatitis Index (FDI). METHODS: Parents of 21 children with atopic dermatitis were enrolled at the Policlinico Hospital in Modena and interviewed on two separate occasions (6/7 days between the interviews). Feasibility was tested by computing the number of missing answers; convergent validity was tested by testing correlation between the scores; reliability was tested in terms of internal consistency and test-retest reproducibility. RESULTS: all the interviewed persons answered to every question. The median severity score was 1.00 (0 – 3), with no significant differences between the two interviews and good level of agreement (weighted kappa=0.604). The IDQOL median score was 9.00 (from 7 to 17, in the first, to 16 in the second interview), with no significant differences between the two interviews; Cronbach's alpha >0.7; Intraclass Correlation Coefficient (ICC) between the first and second assessment =0.95; presence of biases excluded (Bland & Altman method); the coefficient of agreement for each IDQOL item ranged from 0.632 (‘mealtimes') to 1.000 (‘play', “family activities”). The median DFI score was 5 (from 0 to 19, in the first, to 18, in the second interview), with no significant differences between the two interviews, Cronbach's alpha >0.9, ICC between the first and second assessment =0.99, the presence of biases excluded; coefficients of agreement computed for each item ranged from 0.638 (‘feeding') to 0.908 (‘expenditure'). The convergent validity between these instruments was satisfactory, with high and statistically significant correlation coefficients. CONCLUSION: The Italian version of IDQOL and DFI is feasible, valid and reliable. These instruments can be used to evaluate QOL of young patients with atopic dermatitis and their families and can be used to assist decisions on treatment and health-care resource allocation.