OBJCETIVE: To evaluate the basic knowledge level of DM (General manager of the Hospital-GMH- and Chief of clinical service-SCS-) about the application of PE/HE tool as influence characteristics in decision make as well as main advantages and obstacles. METHODS: A transversal survey was perform. In a not related forum, DM were invitated to complete a self-report questionnaire about utilization of concepts of PE/HE in local health care decision make. The main inclusion criteria was the DM taken part in the process of evaluation inclusions of drugs on the basic formulary. Descriptive and multivariate analysis test were applied. RESULTS: A total of 139 questionnaires were included for the analysis. Male 76.98%, the mean of (SD): age 48.28 (+6.35), time of labour experience 19.5 (+7.02).The 30.22% were SCS and 14.39% were GMH. The more important characteristics for inclusions of drugs on the basic formulary are efficacy (82.73%) and safety and tolerability (76.94%).The PE/HE was fith (64.03%). 44.60% had training in PE/HE topics. Cost-benefit was the concept mentioned more frecuently (75.54%). The 68.35% used PE/HE for inclusions of drugs on the basic formulary. The probability of using PE/HE are 3.97 times steal high if DM have taken PE/HE course. The perception of the group of the advantages de PE/HE help them to optimize the resource (54.68%) and to give validation and realiable information (7.91%). About the obstacle of use of PE/HE, DM mentioned the difficult of access of the PE/HE (36.20%) and lack of training (20.69%). A low percentage of participate wrote correct the concepts of PE/HE. CONCLUSIONS: It is important to strengthen the knowledge and utilization of the PE/HE tools in Mexican DM.