OBJECTIVE: To set up regional assistant systems, integrate health resources and advocate high-quality health service, Department of Health in Taiwan promotes the 4th Health Network- New Era Health Care Program in central of Taiwan. One of the major issues is to promote public health education. We set up an educational program to promote appropriate medication concept to the public and students in communities in central of Taiwan. METHODS: Supported by Department of Health and conducted for one year, this was a prospective program consisting of training workshops for community pharmacists, developing and implementing surveys, and public educational promotion. The major issues of public educational promotions include appropriate use of medication, especially those about general medication use, antimicrobial agents and being alert against drug abuse. Even though 34 community pharmacists were recommended from four pharmacy associations in central Taiwan and participated in the training workshops, only 8 pharmacists were qualified as instructor pharmacists according to the results of questionnaire and realistic demonstration after training and evaluating. During 3 months, we held 13 promotions; 6 of them were held in communities and 7 in schools. To evaluate the outcomes of promotions, we conducted a pre- and post- promotion survey via questionnaires. Questionnaires included general information, medication information resources and medication knowledge. RESULTS: A total of 226 participates in communities were distributed with 115 post- promotion survey (51%) and of 475 participates in schools were distributed with 410 (86%) post-promotion survey. The pre-promotion results showed that 57.07% community participators and 77.48% students got medication information from more than 2 sources. After promotions, the results showed that medication knowledge improved significantly in schools and community participators (p<0.05). CONCLUSIONS: We can find out that it sure is a good opportunity for pharmacists to contact the public through well-designed promotion activities and benefit the healthcare systems.