OBJECTIVES

: HeartQoL is a proven reliable and valid ischemic heart disease (IHD) – core questionnaire in China among patients with IHD including angina, myocardial infarction (MI) and heart failure (HF). This study aimed to map HeartQoL to EQ-5D to provide the specific patients’ health status and mapped health utility with one instrument.

METHODS

: A cross-sectional study was conducted by investigating patients with IHD (angina, MI and HF) in China using Chinese version HeartQoL and EQ-5D. Data based on the total group were fitted to two linear regression models. In these two models, the utility scores derived from EQ-5D was set as dependent variable, and the HeartQoL total score and the subscales (physical and emotional) scores as independent variables, respectively. The two models were compared via modelling fitting statistics.

RESULTS

: In total, 406 IHD patients were enrolled from three hospitals in China. The mean HeartQoL global score for the total group was 1.75 (SD=0.85). While the mean physical and emotional for the total group was 1.65 (SD=0.91) and 1.99 (SD=0.93) respectively. The mean utility calculated by EQ-5D for IHD patients was 0.66 (SD=0.38), compared to 0.95 (SD=0.06) for healthy people. From the linear regression models with HeartQoL total score, the total score was a significant predictor for the EQ-5D utility, with the equation of the model EQ-5D=0.085 – 0.3294× total. In the linear regression models with HeartQoL physical and mental score, both the physical and mental scores were significant predictors for the EQ-5D utility, with an equation of the model EQ-5D=0.0671– 0.2091 × physical – 0.1248 × mental.

CONCLUSIONS

: As the first effort to map HeartQoL to EQ-5D, the linear relationship between HeartQoL and EQ-5D was explored, which could potentially be useful in future HTA decision making process and clinical practice.