The management of chronic diseases in Asia poses a heavy economic burden on the individuals as well as the society. As the essence of health care costs for chronic diseases is gradually increasing in Asian countries, the health resource allocation is becoming a hard decision to attain for the organization/government. At this period of time, patients’ willingness to pay has become an important field of policy attention. To get any health resource allocation, it is necessary to perform a cost-effective analysis and considering the disease burden. A cost-effective analysis estimates the incremental cost-effectiveness ratio (ICER) by comparing between the two interventions. In practice, many economic evaluations adopted 1 to 3 times of the specific country’s gross domestic product per capita as the willingness-to-pay (WTP) per quality-adjusted life-years (QALY) threshold. Some other popular approach used to determine the cost-effectiveness threshold is through the utilization of contingent valuation which could offer valuable data to policymakers on the magnitude of individuals’ preferences and may better reflect societal values. Though the co-payments by patients themselves reduces the extra demand produced by free-of-charge provision of health care, it imposes an excessive financial burden among people on low incomes and older people etc. The societal WTP for healthcare benefits have been considered to distribute healthcare resources. WTP/QALY ratios should be lesser than proposed thresholds to decide whether it is cost-effective or not.