OBJECTIVES::  The objective of this study was to compare the intracorporeal anastomosis (IA) and the extracorporeal anastomosis (EC) in the right laparoscopic hemicolectomy to evaluate the short-term outcomes of the two techniques. METHODS:: A systematic review was performed in Pubmed, Embase, Scopus and Web of Science, to identify studies comparing the outcomes between AI and AE in right laparoscopic hemicolectomy. The outcomes evaluated were length of stay, operative time, blood loss, intestinal function recovery, wound infection, ileus or bowel obstruction, anastomotic leakage, mortality, reoperation, 30-day readmission and overall sort-term morbidity. The meta-analysis and the quality assessment was performed in Revman v. 5.3 software (The Cochrane Collaboration). RESULTS:: A total of 143 records were indentified. 15 studies with a total of 1787 patients, who underwent laparoscopic right colectomy for malignant and benign disease, were included in this systematic review and meta-analysis. Length of stay (MD – 0.73 days, 95%CI - 0.94 to - 0.51; p < 0,00001) and time to intestinal function recovery (MD - 0.53 days, 95%CI - 0.57 to - 0.48; p < 0,00001) were shorter in IA patients. The estimated blood loss (MD - 10.18 ml, 95%CI - 10.8 to - 9.56; p < 0,00001) was lower in IA patients. There were no differences in operative time, wound infection, ileus or bowel obstruction, bleeding, anastomotic leakage, reoperation, 30-day readmission, overall sort-term morbidity and mortality. CONCLUSIONS:: Laparoscopic right hemicolectomy with IA is associated with shorter length of stay, faster intestinal function recovery and lower blood loss, although there was no difference in the overall morbidity.