OBJECTIVES::  to present the results of an analysis of cost per patient per year considering the direct costs of an organisational system that provides monitoring services and prevention of pre-dialysis. METHODS::  the study population was defined as being the ambulatory clinical centre (ACC) patients with CKD, which was divided into four subgroups categorised according to additional morbidities, namely arterial hypertension (AH) and/or diabetes mellitus (DM). For costs, there are initiatives from the Ministry of Health (MH) in Brazil. In its manual for the National Program of Cost Management (ref. 2006), the ministry highlighted the importance of establishing methodological criteria for funding to obtain data on health expenditures. The cost estimation was conducted by employing the reciprocal allocation method, valuing the economic classification of costs criteria. To estimate the variability of costs, given the possible fluctuations of both the demand and the expenses, a Monte Carlo simulation was performed with 100,000 iterations, using the licensed software @RISK v.7.5.1. These data were used for the calculation. Therefore, all previous values to December 2014 were adjusted for December 2016. RESULTS::  the simulated total costs per patient per year for the ACC averaged between US$ 316.11 (SD=US$169.45) for CKD and US$1,349.99 (SD=US$520.76) for CKD+AH+DM. The study shows that the subgroup with greater cost to the ACC (CKD+AH+DM) was between US$434.74 and US$2,464.86 per patient per year. CONCLUSIONS:: the ACC provides micro-regional health coverage for prevention and monitoring of chronic non-communicable diseases and, in the context of the presented results, it is possible to expand the study model to obtain cost variations from operations in different Brazilian regions. This would deliver more accurate and relevant information for budget distribution, and help solve the dilemmas of public spending efficiency problems in health care in a very large country with distinct regional characteristics.